Prospective investigation of nasal mupirocin, hexachlorophene body wash, and systemic antibiotics for prevention of recurrent community-associated methicillin-resistant Staphylococcus aureus infections.

نویسندگان

  • Loren G Miller
  • Jennifer Tan
  • Samantha J Eells
  • Esther Benitez
  • Allen B Radner
چکیده

Recurrent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infections are an increasingly common problem. However, there are no data on the efficacy of decolonization regimens. We prospectively evaluated 31 patients with recurrent CA-MRSA skin infections who received nasal mupirocin, topical hexachlorophene body wash, and an oral anti-MRSA antibiotic. The mean number of MRSA infections after the intervention decreased significantly from baseline (0.03 versus 0.84 infections/month, P = <0.0001). This regimen appears promising at preventing recurrent CA-MRSA infections.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 56 2  شماره 

صفحات  -

تاریخ انتشار 2012